DESCRIPTION OF COURSES
BIO 604 GENE REGULATION (3L+0P) III
To provide knowledge about the genome organization, gene expression and regulation in prokaryotes and eukaryotes.
Prokaryotic genome organization and gene clustering; Control of gene expression in Prokaryotes: Bacterial RNA polymerase, Promoters and their properties, Operon concept, lac operon, trp operon, ara operon, various controls of gene expression regulation: Autogenous regulation, Attenuation; Patterns of gene expression control in bacteriophage lambda.
Eukaryotic gene regulation: fundamentals and complexity, Chromatin structure and control of gene expression. Structural motifs in eukaryotic transcription factors.
RNA editing; RNA-interference; Signal transduction and gene regulation in plant development and stress responses.
Epigenetic control of gene expression.