DESCRIPTION OF COURSES

Close

GP 530 QUANTITATIVE GENETICS                                                                     (4L+1P) I

Objective
To impart theoretical knowledge and computation skills regarding component of variation and variances, scales, mating designs and gene effects.

Theory

UNIT I
Probability and its application in genetic analyses; Random variables and Probability distributions.

UNIT II
Genotypic and Phenotypic variation. Genetic component analyses; Partitioning of main effects and variances – ANOVA-MANOVA.

UNIT III
General concepts of gene action – single and multigene models –genetical parameters and their estimations. Heritability & components of gene action. Linkage & Linkage Disequilibrium. Inbreeding and covariance between relatives.

UNIT IV
Mating systems and designs; Combining ability – effects and variance; Genetic divergence. Heterosis; Populations- concepts and their improvement approaches.

Practicals
Problems on multiple factors inheritance - Partitioning of variance -Estimation of heritability and genetic advance - Covariance analysis - D2 analysis - Grouping of clusters and interpretation
- Cluster analysis - Construction of cluster diagrams and dendrograms - interpretation - Diallel
analysis: Hayman’s graphical approach - Diallel analysis: interpretation of results - NCD and their interpretations - Line x tester analysis and interpretation of results - Estimation of heterosis: standard, mid-parental and better-parental heterosis - Estimation of inbreeding depression - Generation mean analysis: Analytical part and Interpretation – Estimation of different types of gene actions. Partitioning of phenotypic variance and co-variance into components due to genotypes, environment and genotype x environment interactions.

Suggested Readings